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Gutfix 8 Licap is a prescription medicine used to treat constipation and irritable bowel syndrome (symptoms include abdominal pain, cramping, bloating, and diarrhea or constipation). It works by increasing the secretion of fluids in the intestine, thereby making the stool soft and easier to pass. Gutfix 8 Licap is taken after meals to avoid nausea in a dose and duration as advised by the doctor. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine. The most common side effects are nausea, diarrhea, headache, abdominal pain, and flatulence. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause diarrhea, so it is better to take plenty of fluids while taking this medicine as it may help to prevent dehydration. Lifestyle modifications like having fiber rich diet and regular exercise can help you to get better results. Before taking this medicine, you should let your doctor know if you have liver and kidney problems. Pregnant or breastfeeding women should also consult their doctor. You may have difficulty in breathing after taking this medicine which generally resolves within three hours but may recur with repeat dosing.
Uses of Gutfix 8 Licap
Side effects of Gutfix 8 Licap
Common
How to use Gutfix 8 Licap
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gutfix 8 Licap is to be taken with food.
How Gutfix 8 Licap works
Gutfix 8 Licap increases the secretion of fluids in the intestine, which in turn increases the motility of the intestine, thereby making the stool soft and easier to pass.
What if you forget to take Gutfix 8 Licap?
If you miss a dose of Gutfix 8 Licap, skip it and continue with your normal schedule. Do not double the dose.
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Brief Description
Indication
Irritable Bowel Syndrome with Constipation (IBS-C), Chronic idiopathic constipation, Opioid-induced Constipation (OIC) in adults with chronic non-cancer pain
Administration
Should be taken with food.
Adult Dose
Oral Chronic idiopathic constipation Adult: 24 mcg bid daily. Irritable Bowel Syndrome With Constipation 8 mcg twice daily. Opioid-Induced Constipation Treatment in patients with chronic noncancer pain 24 mcg bid daily. Hepatic impairment Mild: Dose adjustment not necessary Moderate (Child-Pugh B): Chronic idiopathic or opioid-induced constipation, 16 mcg PO q12hr; irritable bowel syndrome with constipation (IBS-C), no dosage adjustment required Severe (Child-Pugh C): Chronic idiopathic or opioid-induced constipation, 8 mcg PO q12hr; IBS-C, 8 mcg PO q24hr
Child Dose
Safety and efficacy not established
Contraindication
History of mechanical GI obstruction.
Mode of Action
Lubiprostone is a locally acting chloride channel activator that enhances a chloride-rich intestinal fluid secretion without altering sodium and potassium concentrations in the serum. Lubiprostone acts by specifically activating ClC-2, which is a normal constituent of the apical membrane of the human intestine. By increasing intestinal fluid secretion, Lubiprostone increases motility in the intestine, thereby facilitating the passage of stool and alleviating symptoms associated with chronic idiopathic constipation.
Precaution
Safety has not been established in pregnant women. Not to be used in patients with severe diarrhoea. Lactation: Unknown whether drug is excreted in breast milk; because lubiprostone increases fluid secretion in the intestine and intestinal motility, monitor breastfeeding infants for diarrhea
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